منابع مشابه
Maternal microchimerism in the livers of patients with Biliary atresia
BACKGROUND Biliary atresia (BA) is a neonatal cholestatic disease of unknown etiology. It is the leading cause of liver transplantation in children. Many similarities exist between BA and graft versus host disease suggesting engraftment of maternal cells during gestation could result in immune responses that lead to BA. The aim of this study was to determine the presence and extent of maternal ...
متن کاملMaternal HLA class I compatibility in patients with biliary atresia.
Biliary atresia (BA) is an inflammatory cholangiopathy of unknown etiology. Maternal microchimerism has been identified in the livers of patients with BA. We analyzed the human leukocyte antigen (HLA) compatibility between 57 BA patient-mother pairs and 50 control-mother pairs. The HLA class I matching was significantly more frequent in BA pairs (odds ratio [OR]=2.46) than controls. Similar res...
متن کاملBiliary atresia
Biliary atresia (BA) is a cholangiodestructive disease affecting biliary tract, which ultimately leads to cirrhosis, liver failure and death if not treated. The incidence is higher in Asian countries than in Europe. Up to 10% of cases have other congenital anomalies, such as polysplenia, asplenia, situs inversus, absence of inferior vena cava and pre-duodenal portal vein, for which we have coin...
متن کاملThe Role of Appendix in the Management of Biliary Atresia Associated with Bowel Atresia
Biliary atresia is characterized by the progressive obliteration of extra- and intrahepatic biliary duct system leading to the obstruction of bile flow in infancy. The cause(s) of biliary atresia remain unclear and many surgical options for bypassing the atretic segment have been described.1-3 Biliary atresia may be associated with small bowel atresia. The surgical interventions for biliary dr...
متن کاملBiliary atresia.
Biliary atresia is a neonatal obstructive cholangiopathy characterized by a fibrosclerosing obliteration of the extrahepatic bile duct that uniquely presents in the first months of life (1). The condition occurs in approximately 1 in 8,000 to 1 in 15,000 live births and accounts for 30% of all cases of cholestasis in young infants. Biliary atresia is the most frequent cause of chronic end-stage...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chimerism
سال: 2014
ISSN: 1938-1956,1938-1964
DOI: 10.4161/chim.28576